COURSE UNIT TITLE

: LABORATORY ANALYSIS IN CLINICAL TOXICOLOGY

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
TOK 6054 LABORATORY ANALYSIS IN CLINICAL TOXICOLOGY ELECTIVE 1 2 0 6

Offered By

Toxicology

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR YEŞIM TUNÇOK

Offered to

Toxicology

Course Objective

Sample collection of body fluids in acute and chronic toxicity, used in diagnosis of toxicological analyzes, specificity and sensitivies, therapeutic Drug Monitoring (TDM), toxicologic analysis in urine, found on the level of knowledge and skill areas

Learning Outcomes of the Course Unit

1   Body fluids in the diagnosis of acute and chronic toxicity to define which samples will be taken
2   Correlation between blood levels and clinical signs of poisoning agent
3   Define the specificity and sensitivity of toxicological analysis of body fluids
4   Evaluate toxicology laboratory manual

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Good Laboratory Practices-1
2 Good Laboratory Practices-2
3 Sampling principles in poisoning
4 Extraction methods in poisonings
5 Methods used in Toxicology Laboratuary-1
6 Methods used in Toxicology Laboratuary-2
7 Importance of toxicology laboratory in acute toxicity
8 Importance of toxicology laboratory in chronic toxicity
9 Therepeutic drug Monitoring and commentory
10 Nomograms in toxicology
11 Toxicologic anlaysis in urine and sampling principles
12 Toxicologic analysis principles in heavy metal poisonings
13 Toxicologic analysis principles in pesticide poisonings
14 Toxicologic analysis principles in gas poisonings
15 Guidelines in toxicology laboratory
16 Final exam

Recomended or Required Reading

Textbook(s):
1. Goldfrank LR, Flomenbaum NE, Lewin NA, Weisman RS, Howland MA, Hoffman RS, eds. Goldfrank s Toxicologic Emergencies, 9th edition, USA, The McGraw-Hill Companies, 2010.
2. Olson KR. Poisoning and Drug Overdose. 4th edition, McGrawHill, USA, 2004.
3. POISINDEX® System: Klasco RK (Ed): POSINDEX® System. Thomson Micromedex, Greenwood Village, Colorado
4. Systematic Toxicological Analysis: Laboratory Guidelines.
References:

Planned Learning Activities and Teaching Methods

All the strategies are located Assesment methods and Total work load

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 PRF PERFORMANCE
2 FIN FINAL EXAM
3 FCG FINAL COURSE GRADE PRF * 0.40 + FIN*0.60
4 RST RESIT
5 FCGR FINAL COURSE GRADE (RESIT) PRF * 0.40 + FCGR*0.60


Further Notes About Assessment Methods

None

Assessment Criteria

To be succesful in final exam and practice exam.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

yesim.tuncok@deu.edu.tr Tel: 4123903

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 15 1 15
Practice (Reflection) 15 2 30
Preparations before/after weekly lectures 15 3 45
Preparation for final exam 1 20 20
Reading 1 20 20
Final 1 10 10
TOTAL WORKLOAD (hours) 140

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12PO.13PO.14
LO.135555322222533
LO.235555322222333
LO.335555322233333
LO.435555322222223

CONTACT INFORMATION
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Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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