COURSE UNIT TITLE

: ANTICANCER CHEMOTHERAPY AND NOVEL TREATMENT MODALITIES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
ONK 6089 ANTICANCER CHEMOTHERAPY AND NOVEL TREATMENT MODALITIES ELECTIVE 2 0 0 6

Offered By

Basic Oncology

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR ILHAN ÖZTOP

Offered to

Basic Oncology
Basic Oncology

Course Objective

To give information about the anti-cancer treatment methods and chemotherapeutic agents to the basic science students and hence to provide a cooperation between basic and clinical science.

Learning Outcomes of the Course Unit

1   Knows the main cancer treatment methods and anti-cancer agents
2   Be able to recognize structure and mechanisms of anti-cancer agents.
3   Knows the clinical use of anti-cancer agents in the treatment of specific types of cancer.
4   Knows the general treatment methods that used in clinical oncology practice.
5   Be able to criticize and plan and clinical oncology studies

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Introduce to chemotherapy and new treatment methods
2 Cell proliferation kinetics and clinical applications
3 Chemotherapeutic drug development, pharmacodynamic and pharmacokinetic studies
4 Chemotherapeutic drug development, Phase II and III studies
5 New targets in the era of anticancer agents
6 Principal anti-cancer agents and their side effects
7 Main principles of chemotherapy application in clinical setting (Elderly)
8 Main principles of chemotherapy application in clinical setting (Childhood)
9 Drug sensitivity and resistance
10 Biological response modifiers, Growth factors, and Dendritic Cell Based Therapy
11 Gen therapy and other new treatment methods
12 Use of hormones in the treatment of cancer
13 Cancer prevention and cancer vaccines
14 Differentiating agents and TNF

Recomended or Required Reading

1. Cancer Principles and. Practice of Oncology 7th. Edition Vincent Devita, Samuel Hellamas, Cancer Medicine 5.th edition Samuel Hellamas
2. Manual of Clinical Oncology. D.K. Hossfeld, C.D. Sherman, R.R. Love, F.X. Bosch Springer- Verlag, 2009 Sixth Edition.
3. Pathologic Basis of Disease. Vinay Kumar, Abul K. Abbas, Nelson Fausto, Elsevier Saunderss, 2005 Seventh Edition
4. Molecular Mechanism of Cancer. Georg F. Weber, Springer 2007
5. The Biology of Cancer Robert A. Weinberg, Gariand Science 2007
. Use and Interpretation of Laboratory Tests in Oncology. Douglas C. Aziz, Specialty Laboratories. Third edition 1998
7. Chemosensitivity Testing in Oncology. U. Rainhold W. Tilgen Springer 2003
8. Diagnostic Approach to Clinical Oncology Mario W. Fiorentino PICCIN 1999
9. Molecular Biology in Cancer Medicine. Razelle Kurzrock, Moshe Talpaz, Martin Dunitz 1995.

Planned Learning Activities and Teaching Methods

Theoretical and practical courses done, Giving practical examples about the spesific treatment methods used in the certain type of cancer (eg breast cancer, lung cancer), working on the chemotherapeutic, biological and targeted agents, intermediate and final exam done.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 PRF PERFORMANCE
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE MTE * 0.20 +PRF * 0.20 + FIN* 0.60
5 RST RESIT
6 FCGR FINAL COURSE GRADE MTE * 0.20 +PRF * 0.20 +RST* 0.60


Further Notes About Assessment Methods

None

Assessment Criteria

1. To know the main cancer treatment methods and anti-cancer agents
2. Be able to recognize structure and mechanisms of anti-cancer agents.
3. To know the clinical use of anti-cancer agents in the treatment of specific types of cancer.
4. The general treatment methods that used in clinical oncology practice will be evaluate in applied lessons.
5. To question the making of intermediate and searching capabilities related to clinical oncology researchs will be evaluate with midterm and final exam.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

ilhan.oztop@deu.edu.tr 0 232 4125801

Office Hours

on Wednesday at: 13.30-16.30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 15 2 30
Tutorials 15 2 30
Preparation for midterm exam 1 20 20
Preparation for final exam 1 34 34
Preparing assignments 1 30 30
Final 1 3 3
Midterm 1 3 3
TOTAL WORKLOAD (hours) 150

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11
LO.15555555
LO.25555555555
LO.355555555
LO.455555
LO.555555