COURSE UNIT TITLE

Offered By

Basic Oncology

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR SAFIYE AKTAŞ

Offered to

Basic Oncology
Doctorate Program Rare Diseases
Basic Oncology

Course Objective

Define the basic oncology, cancer etiology, carcinogenesis, cell cycle and cancer relationship, differentiation and transformation of the molecular mechanisms of cancer development and understanding of the role. Mechanisms of cell death, angiogenesis, invasion and metastasis, the Importance of signaling pathways in cancer, oncogene and tumor suppressor genes is the understanding of the importance of cancer diagnostic, treatment and monitoring. Molecular Basis of anticancer therapy is to understand the specific examples of types of cancer. In laboratory lessons cancer cell culture, differentiation of cancer cell culture model, western blot practice, tumor tissue, DNA, RNA Isolation, Real-time PCR and mutation analysis in understanding of cancer diagnosis.

Learning Outcomes of the Course Unit

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Recomended or Required Reading

Textbook(s): Use and Interpretation of Laboratory Tests in Oncology. Douglas C. Aziz, Specialty Laboratories. Third edition 1998
2. Chemosensitivity Testing in Oncology. U. Rainhold W. Tilgen Springer 2003
3. Diagnostic Approach to Clinical Oncology Mario W. Fiorentino PICCIN 1999
4. Molecular Biology in Cancer Medicine. Razelle Kurzrock, Moshe Talpaz, Martin Dunitz 1995.
5. Tumor Models in Cancer Research Beverly A. Teicher Humana Pres 2002
6. AJCC Cancer Staging Handbook.Irvin D. Fleming. Lippincott Willams & Wilkins 1998
7. Manual of Clinical Oncology. D.K. Hossfeld, C.D. Sherman, R.R. Love, F.X. Bosch Springer- Verlag, 1990 Fith Edition.
8. Pathologic Basis of Disease. Vinay Kumar, Abul K. Abbas, Nelson Fausto, Elsevier Saunderss, 2005 Seventh Edition
9. Molecular Mechanism of Cancer. Georg F. Weber, Springer 2007
10. The Biology of Cancer Robert A. Weinberg, Gariand Science 2007

Planned Learning Activities and Teaching Methods

Theoretical and practical courses done, a certain type of cancer (eg breast cancer, lung cancer), the basic method used in oncology (RT-PCR, Sequencing), a parameter study of the diagnostic or prognostic assignment given in scientific format, intermediate and final exam done.

Assessment Methods

Further Notes About Assessment Methods

None

Assessment Criteria

1. Being able to express in general terms the basic oncology, prepared by a particular type of cancer (eg breast cancer, lung cancer), the basic method used in oncology (RT-PCR, Sequencing) for diagnostic or prognostic assignment of a parameter with the preparation work will be assessed.
2. The general methods used in oncology to know and basic practical courses will be evaluate in applied lessons.
3. To question the making of intermediate and searching capabilities related to basic oncology researchs will be evaluate with midterm and final exam.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

safiye.aktas@deu.edu.tr 0 232 4125891/5801

Office Hours

on Monday at: 13.30-16.30

Work Placement(s)

None

Workload Calculation

Contribution of Learning Outcomes to Programme Outcomes