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Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS MIK 6040 CELLULAR AND MOLECULAR IMMUNOLOGY ELECTIVE 3 2 0 12

Offered By

Microbiology

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR IBRAHIM MEHMET ALI ÖKTEM

Offered to

Doctorate Program Rare Diseases Microbiology

Course Objective

Understand the immune system components, immun responses and contorl mechanisms involved in infectious disease by integrative way from molecule to the system.

Learning Outcomes of the Course Unit

1   Identify components of innate immune responses 2   Antigen recognition structures related to them and to understand the molecular mechanisms of genetic regulation of antigen presentation 3   Understand the ontogeny of theLenfosit, responses occurred after the stimulation of the T and B cell receptor, to discuss these mechanisms and regulationu 4   Define the molecular mechanism of immun system effector mechanisms and their responses 5   Knowing that describes medical conditions related to the immune system 6   Be able to match up basic vaccinology knowledge and cellular and molecular mechanisms

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description 1 Properties and Overview of Immune Responses 2 Cells and Tissues of the Immune System Antibodies and Antigens 3 Major Histocompatibility Complex Molecules and Antigen Presentation to T Lymphocytes 4 Lymphocyte Development and Antigen Receptor Gene Rearrangement, Activation of T Lymphocytes 5 B Cell Activation and Antibody Production 6 Immunological tolerance 7 Cytokines Natural immune responses 8 Effector mechanisms of cellular immune responses 9 Effector Mechanisms of Humoral Immunity, Immunity to Microbes 10 Transplantation immunology Tumor immunology 11 Hypersensitivity reactions and autoimmunity 12 Congenital and acquired Immunodeficiencies Traditional and new approaches in vaccine preparation

Recomended or Required Reading

Abbas, Lichtman & Pillai. Cellular and Molecular Immunology 7th Ed, Saunders, Elsevier, 2012

Planned Learning Activities and Teaching Methods

Theoretical lessons and practices, as well as one of the selected article by the instructor for that year are examined in detail and presented.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA 1 ASG ASSIGNMENT 2 FIN FINAL EXAM 3 FCG FINAL COURSE GRADE ASG * 0.10+FIN* 0.90 4 RST RESIT 5 FCGR FINAL COURSE GRADE (RESIT) ASG * 0.10+RST* 0.90

Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

hakan.abacioglu@deu.edu.tr Tel: (232) 412-4504

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours) Student Presentations 1 2 2 Practice (Reflection) 7 2 14 Lectures 30 2 60 Preparations before/after weekly lectures 30 2 60 Preparing assignments 1 20 20 Web Search and Library Research 30 2 60 Reading 6 3 18 Preparation for final exam 1 36 36 Preparing assignments 1 20 20 Final 1 2 2 TOTAL WORKLOAD (hours) 292

Contribution of Learning Outcomes to Programme Outcomes

PO/LO PO.1 PO.2 PO.3 PO.4 PO.5 PO.6 PO.7 PO.8 PO.9 PO.10 PO.11 PO.12 LO.1 5 5 2 LO.2 5 5 LO.3 5 5 LO.4 5 5 LO.5 5 5 2 3 LO.6 4 5