COURSE UNIT TITLE

: INTRODUCTION TO CARSINOGENESIS

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
ONK 5045 INTRODUCTION TO CARSINOGENESIS COMPULSORY 1 0 0 2

Offered By

Basic Oncology

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR DOCTOR ZEKIYE SULTAN ALTUN

Offered to

Basic Oncology
Basic Oncology

Course Objective

The aim of this course is to understand the factors which contribute to carcinogenesis by viral, chemical and physical carcinogenic agents and concepts, mechanisms, and to provide information on the steps of the formation of cancer.

Learning Outcomes of the Course Unit

1   Capable of understanding the biological differences and characterization of molecular biologic features came from viral, physical and chemical carcinogenic agents effective in carcinogenesis.
2   Be able to explain relationship cancer development with different carcinogenic agents
3   Be able to know and learn viral carcinogenic agents and their roles in carcinogenesis.
4   Be able to know and learn chemical carcinogenic agents and their roles in carcinogenesis.
5   Be able to know and learn physical carcinogenic agents and their roles in carcinogenesis.
6   Be able to understand the molecular characteristics and terms of stages of carcinogenesis and carcinogenesis related genes and clinical image.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 The concept of carcinogenesis
2 Theories of carcinogenesis
3 Chemical carcinogenesis
4 Chemical carcinogenesis and mechanisms
5 Viral carcinogenesis (DNA viruses and mechanisms of carcinogenesis)
6 Viral carcinogenesis (RNA viruses and mechanisms of carcinogenesis)
7 Physical carcinogenic agents and mechanisms
8 Physical carcinogenic agents and mechanisms
9 homework presentations
10 Tobacco Smoking and carcinogenesis
11 Genetic susceptibility to carcinogenesis
12 Determination of carcinogenic agents
13 Carcinogenic agents and DNA repair
14 Multistep carcinogenesis
15 Final Exam

Recomended or Required Reading

1. Principles and Practise of Oncology 7th edition. Vincent T De Vita 2005.
2. Diagnostic Approach to Clinical Oncology Mario W. Fiorentino PICCIN 1999
3. Molecular Biology in Cancer Medicine. Razelle Kurzrock, Moshe Talpaz, Martin Dunitz 1995.
4. AJCC Cancer Staging Handbook.Irvin D. Fleming. Lippincott Willams & Wilkins 1998
5. Manual of Clinical Oncology. D.K. Hossfeld, C.D. Sherman, R.R. Love, F.X. Bosch Springer- Verlag, 1990 Fith Edition.
6. Pathologic Basis of Disease. Vinay Kumar, Abul K. Abbas, Nelson Fausto, Elsevier Saunderss, 2005 Seventh Edition
7. Molecular Mechanism of Cancer. Georg F. Weber, Springer 2007
8. The Biology of Cancer Robert A. Weinberg, Gariand Science 2007

Planned Learning Activities and Teaching Methods

Theoretical Lectures, Giving a homework, Working for exams, Reading practices

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 PRF PERFORMANCE
2 FIN FINAL EXAM
3 FCG FINAL COURSE GRADE PRF * 0.40 + FIN*0.60
4 RST RESIT
5 FCGR FINAL COURSE GRADE (RESIT) PRF * 0.40 + FCGR*0.60


Further Notes About Assessment Methods

None

Assessment Criteria

Learning outcomes will be assessed with classical questions of final exams. The homework on the topic of molecular mechanisms of special cancers related to viral, chemicals and physical agents will help in evaluating the learner understood the topics or not.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

zekiye.altun@deu.edu.tr 0 232 412820471/5801

Office Hours

on Tuesday at: 13.30-16.30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 1 14
Preparations before/after weekly lectures 15 1 15
Preparing assignments 1 10 10
Preparation for final exam 1 10 10
Final 1 1 1
TOTAL WORKLOAD (hours) 50

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10
LO.155
LO.255
LO.355
LO.455
LO.555
LO.655

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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