COURSE UNIT TITLE

: INTRODUCTION TO CANCER BIOCHEMISTRY

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
ONK 5034 INTRODUCTION TO CANCER BIOCHEMISTRY COMPULSORY 2 0 0 4

Offered By

Basic Oncology

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR DOCTOR HILAL KOÇDOR

Offered to

Molecular Medicine
Basic Oncology
Basic Oncology

Course Objective


The goals of this course are to introduce the student to the basic concepts of the mechanisms of carcinogenesis and to begin applying these concepts to research problems.

Learning Outcomes of the Course Unit

1   Synthesizing, analysing with qualitative an quantitative data, interpretation and evaluation of collected information about normal and cancer cells.
2   Acquire basic and clinical cancer knowledge
3   Identifiable the carcinogens and have expertise in the theorical basis of carcinogenesis.
4   Analyse at the critical level the basic principles of cancer cells and cancer biology.
5   Synthesize the knowledge on proliferation, differantiation and apply it to new situations.
6   Creating the scientific report from obtained results and presentation these results as verbal and visual.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Introduction, Cancer phenotype
2 Cell cycle and signaling in cancer
3 Carbohyrate metabolism in cancer
4 Amino acid metabolism in cancer
5 Protein metabolism in cancer
6 Nucleic asid metabolism in cancer
7 Lipid and cholesterol metabolism in cancer
8 Cancer and epigenetic
9 Chemical carcinogens
10 Cytotoxic spies
11 Nutrition in cancer ,Vitamins and trace elements in cancer
12 Research methods in cancer, Metabolic changes in cancer

Recomended or Required Reading


1. Principles of Cancer Biology, Kleinsmith, (2005).
2. Nelson DL, Cox MM. Lehninger Principles of Biochemistry. Third editon Worth Publishers, New York, 2000.
3. Devlin TM. Texbook of Biochemistry with Clinical Correlations.Fifth edition, Wiley-Liss, New York, 2002.
4. Meisenberg G, Simmons WH. Principles of Medical Biochemistry. Mosby Inc., St. Louis, Missouri, 1998.
5. Baynes J, Dominiczak MH. Medical Biochemistry. Mosby Inc.,London,1999.
6. Marks DB, Marks AD, Smith CM. Basic Medical Biochemistry. A Clinical Approach. Williams & Wilkins, Baltimore, Maryland, 1996.
7. The Biology of Cancer Robert A. Weinberg, Gariand Science 2007,
8. Tumor Biology. G.A.Dalglenish M. Browning Cambridge 1996

Planned Learning Activities and Teaching Methods



The course will be run in an integrated way-winding theory with case discussion. The methods of learning will be interactive.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 ASG ASSIGNMENT
2 FIN FINAL EXAM
3 FCGR FINAL COURSE GRADE ASG * 0.40 + FIN* 0.60
4 RST RESIT
5 FCGR FINAL COURSE GRADE (RESIT) ASG * 0.40 + RST* 0.60


Further Notes About Assessment Methods

None

Assessment Criteria


Oral presentation: Each student will give an oral presentation based on a current scientific article related to the week s topic.
Final Paper: The final assignment will be to write a grant proposal focusing on the topics that we have covered in class.
A detailed description of the format and expectations will be given to students following the midterm presentation.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)


Dokuz Eylül University, Institute of Oncology, Department Of Basic Oncology Inciraltı/ Izmir

Office Hours


Wednesday 14.00-15.00

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 30 1 30
Preparation for final exam 20 2 40
Preparing presentations 1 15 15
1 12 12
Final 1 3 3
TOTAL WORKLOAD (hours) 100

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10
LO.15
LO.25
LO.35
LO.45
LO.55
LO.655

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

Copyright 2015 DEÜ. BİD

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