COURSE UNIT TITLE

: BASICS OF TUMOR IMMUNOLOGY

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
ONK 5036 BASICS OF TUMOR IMMUNOLOGY COMPULSORY 1 0 0 3

Offered By

Basic Oncology

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR DOCTOR SAFIYE AKTAŞ

Offered to

Basic Oncology
Basic Oncology

Course Objective

aim of this course is to understand basic principles of tumor immunology, and to learn its role in cancer therapy. Future aspects of tumor immunology is planned to be tought.

Learning Outcomes of the Course Unit

1   Capable of understanding tumor antigens, mechanisms of immune responses to tumor, relationship of immune insuffuciency syndromes and cancer
2   Be able to understand properties of cytokines, B and T lymphocytes, NK cells, regulatory T cells, dendritic cells and their roles in tumor
3   Be able to identfy immunologic escape mechanisms of tumor cell
4   Be able to understand immunotherapy principles
5   Capable of doing laboratory work about immunology

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Defination of Tumor Immunology
2 Principles of Immun System
3 Tumor Antigens
4 HLA System
5 Relationship of HLA System with Cancer
6 Immun Response to Tumor
7 Spontaneous Regression in Cancer
8 Midterm exam
9 Antigen Presentation in Cancer
10 Immunsupression and Cancer
11 Humoral Immunity and Cancer
12 12. Cellular Immunity and Cancer 13. Immunologic Methods in Cancer Diagnosis 14.Escape of cancer cell from Immune System 15. Future Aspects in Cancer Immunotherapy 16. FINAL EXAM

Recomended or Required Reading

1. Molecular Biology in Cancer Medicine. Razelle Kurzrock, Moshe Talpaz, Martin Dunitz 1995.
2. Immunology. Ivan Roitt, Jonathan Brostoff , David Male. Mosby,1998 Fourth Edition
3. Basic & Clinical Immunology. Daniel P. Stites, John D. Stobo, J. Vivian Wells . Appleton& Lange, 1987 Six Edition
4. Dendritic Cell Protocols Stephen P. Robinson, Andrew J. Stagg, Humana Press 2002
5. Molecular Mechanism of Cancer. Georg F. Weber, Springer 2007
6. The Biology of Cancer Robert A. Weinberg, Gariand Science 2007
7. Cellular and Molecular Immunology eds. Abul Abbas, Lichtman Ah, Pober JS. Saunders Company 1991 Philadelphia, USA.
8. Immunology . 4th ed. Ed. Roitt, Brostoft. Mosby, London, 1998.
9. Basic and Clinical Immunology. 6th ed. Eds.Stides, Stobo, Wells. Connecticut USA.

Planned Learning Activities and Teaching Methods

Theoretical Lectures, Giving a homework, Working for exams, Reading practices

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 PRF PERFORMANCE
3 FIN FINAL EXAM
4 FCGR FINAL COURSE GRADE MTE * 0.30 + PRF* 0.30 + FIN* 0.40
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.30 + PRF* 0.30 + RST* 0.40


Further Notes About Assessment Methods

None

Assessment Criteria

Learning outcomes will be evaluated with mid-term and final classical written long-answer questions. It will be reinforced with an assignment in the form of reading and summarizing 5 articles on tumor immunology in a certain type of cancer (eg malignant melanoma, colorectal cancer).

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

safiye.aktas@deu.edu.tr 0 232 4125891/5801

Office Hours

on Monday at: 13.30-16.30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Tutorials 0
Lectures 14 1 14
Preparation before/after weekly lectures 6 3 18
Preparation for Mid-term Exam 1 10 10
Preparation for Quiz etc. 0
Preparing Group Assignments 0
Preparing Presentations 0
Other (please indicate) 0
Preparation for Final Exam 1 15 15
Preparing Individual Assignments 1 16 16
Ouiz etc. 0
Final 1 1 1
Mid-term 1 1 1
TOTAL WORKLOAD (hours) 75

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10
LO.155
LO.255
LO.355
LO.455
LO.555

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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