COURSE UNIT TITLE

: CANCER AND MOLECULER NUTRITION

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
ONK 5019 CANCER AND MOLECULER NUTRITION ELECTIVE 2 0 0 3

Offered By

Basic Oncology

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR DOCTOR HÜLYA ELLIDOKUZ

Offered to

Basic Oncology
Basic Oncology

Course Objective

Examination of the relationship between cancer and moleculer nutrition in the process of carcinogenesis .The particularly targeted the investigation and discuss of multidisciplinary research topics context of relations cancer, and genomics ,nutrigenetics nutrigenomics, epigenomics
The importance of moleculer epidemiology and moleculer nutrition ,interactions of chemoprevention in the prevention of cancers explaning.
To provide experience in issues related to in vitro conditions of chemoprevention studies . the students Issues in this course about of the project and scientific studies was intended to ensure the adaptation.

Learning Outcomes of the Course Unit

1   capable of outline the relationship between cancer and the molecular nutrition can express (knowledge).
2   Be able to recognize and understand the relationship between Cancer and genetics, nutrigenetics, nutrigenomics understand
3   Be able to identify of tumor biology and nutrient relations (evaluation)
4   Be able to identify relationships of cancer and molecular epidemiology, nutritional epidemiology and interpret (evaluation)
5   Be able to research and inquire about the work of cancer and moleculer nutrition

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Oxidative stress cancer and antioxidants
2 Inflammation cancer and nutrients
3 Epigenetics cancer and Nutritional epigenomics diet
4 Nutrigenetic ,nutrigenomics and cancer
5 Energy balances ,epiobecigenetic genes,metabolomics
6 Apoptosis and Angiogenesis and nutrients
7 Tumour biology and bioactive foods
8 Tumour cell activities and immune-nutrition
9 Gen nutrient relations and The moleculer nutrition approaches to breast, ovarian, prostate,Gastrointestinal cancers and cancer chemoprevention
10 Bioactive nutritional compounds and to share experiences in vitro in working conditions
11 Chemoprevention studies in molecular epidemiology and nutritional epidemiology
12 The future of Alternative Cancer Treatments and preclinical studies

Recomended or Required Reading


Nutrigenetics and Nutrigenomics . A.P.Simopoulos ,JM.Ordovas . Karger 2007 ,
Cancer and Nutrition , Elsevier Saunders,2009
Nutrient and cancer Patient , Oxford University press 2010
Mediteranen and nutrition Uşşak Tif Matbaacılık 2009 (Mediteranen and nutrition , cancer and nutiriton :Rüksan Çehreli ),
R.Çehreli . Moleküler Beslenme ve Kanser . Klinik Aktüel Tıp Onkoloji Özel Sayısı ).2006 .11( 10)
Referanslar: Chemopreventive efficacies of rosiglitazone, fenretinide and their combination against rat mammary carcinogenesis.
Kocdor H, Kocdor MA, Canda T, Gurel D, Cehreli R, Yilmaz O, Alakavuklar M, Guner G.
Clin Transl Oncol. 2009 Apr;11(4):243-9.
H.Kocdor,R.Cehreli,Mali.Kocdor,B.Sis,O.yılmaz,T.Canda,B.Demirkan,H.Resmi, M.Alakavuklar,O.Harmancıoglu . Toxicity Induced By The Chemical Carcinogen 7, 12 Dimethylbenz( A) Anthracene and the Protective Effects of Selenium In Wistar Rats. Journal Of Toxicology and Environmetal Health .part A ,68: 693-701.2005

Planned Learning Activities and Teaching Methods

Theoretical and applied Lectures, in vivo and in vitro conditions in the laboratory observation of the ongoing studies on cancer and nutrient relations
presentation regarding relations between cancer and molecular nutrition by students, giving a homework.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 PRF PERFORMANCE
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE MTE * 0.20 +PRF * 0.20 + FIN* 0.60
5 RST RESIT
6 FCGR FINAL COURSE GRADE MTE * 0.20 +PRF * 0.20 +RST* 0.60


Further Notes About Assessment Methods

None

Assessment Criteria

1. The learner will clearly define outlined cancer and moleculer nutrition which will evaluate with presentations prepared by themselves, homework

2. The learner will assignments related to the cancer and genomic,nutrigenetics,nutrigenomics making the presentation and homework , exam

3. The learner will assignments related to the tumour biology and nutrients, making the presentation,homework, exam

4. The learner will recognize cancer and moleculer epidemiology , nutritional epidemiology studies; will evaluate with homework, prepared presentations by themselves and exam
5. The learner will recognize cancer and moleculer nutrition studies; will evaluate with homework, prepared presentations by themselves and exam

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

ruksan.cehreli@deu.edu.tr,
tel: 4124804

Office Hours

on Tuesday at: Friday 14.30-16.30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 2 28
Tutorials 1 2 2
Preparations before/after weekly lectures 4 2 8
Preparation for midterm exam 1 10 10
Preparation for final exam 1 12 12
Preparing assignments 1 11 11
Final 1 2 2
Midterm 1 2 2
TOTAL WORKLOAD (hours) 75

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10
LO.15555555
LO.255555555
LO.355555555
LO.4555555555
LO.555555555