COURSE UNIT TITLE

: BASICS OF CLINICAL PHARMACOLOGY

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
FAR 5006 BASICS OF CLINICAL PHARMACOLOGY ELECTIVE 1 0 0 2

Offered By

Pharmacology

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR DOCTOR AYŞE GELAL

Offered to

Translational Oncology
Pharmacology
Toxicology
Translational Oncology

Course Objective

To learn general aspects of drugs, to discuss pharmacokinetics and pharmacodynamics of drugs, to discuss mechanism of drug-drug interactions

Learning Outcomes of the Course Unit

1   To learn the role of clinical pharmacology in the fields of education, medical service and reasearch
2   To be able to interpret plasma concentration time graphic after single and multiple dose drug administration; to be able to define dose effect relation and concept of therapeutic index
3   To understand drug development process from the molecule to the counter and explain and interpret legal issues related with drug development
4   To learn and interpret basic information and legal issues related with drug safety
5   To explain the mechanisms of drug interactions (drug-drug interactions, drug-food interactions); to interpret factors influencing these interactions
6   To comprehend the mechanisms of pharmacokinetic and pharmacodynamic changes in special patient groups.
7   To explain the concept of equivalent drug
8   To learn the drugs that undergo TDM
9   To be able to interpret pharmacogenetic and personal drug selection
10   To learn and practice principles of rational drug use

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Introduction of clinical pharmacology
2 Basic consepts in pharmacokinetics and pharmacodinamics
3 Drug development I
4 Drug development 2
5 Ethical and legal aspects in drug development
6 Bioavailability/Bioequavalance
7 Pharmacovigilance
8 The mechanisms in drug interactions
9 Drugs in children and elderly
10 Factors influencing drug use in pregnancy and lactation, Teratogenic drugs
11 Basics of pharmacoeconomic analysis
12 Pharmacogenetics
13 What is rational pharmacotherapy
14 Therapeutic drug monitoring
15 Final exam

Recomended or Required Reading

Kayaalp O. Rasyonel tedavi yönünden Tıbbi Farmakoloji. 12. baskı, Ankara: Feryal matbaacılık; 2009.
2. B. Katzung. Basic and Clinical Pharmacology. McGraw-Hill. 12th ed. 2011.
3. Brunton L, Chabner B, Knollman B. Goodman & Gilman's The Pharmacological Basis of Therapeutics. McGraw-Hill. 12th ed. 2011.
4. Prof. Dr. S. Oğuz Kayaalp. Türkiye'de Klinik Farmakolojinin gelişmesi: olaylar, görüşler ve tavsiyeler. Türk Farmakoloji Derneği Klinik Farmakoloji Çalışma Grubu e-bülteni. Mayıs, 2010.

Planned Learning Activities and Teaching Methods

All the strategies are located Assesment methods and Total work load

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 PRF PERFORMANCE
2 FIN FINAL EXAM
3 FCG FINAL COURSE GRADE PRF * 0.40+ FIN* 0.60
4 RST RESIT
5 FCGR FINAL COURSE GRADE PRF * 0.40+ RST* 0.60


Further Notes About Assessment Methods

A topic of the course outline which is choose with course coordinator must be present as a report

Assessment Criteria

To be succesful in final exam and, to present a topic in course outline as a report

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

ayse.gelal@deu.edu.tr, Tel: 4123904

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 1 14
Preparations before/after weekly lectures 14 2 28
Preparing presentations 1 6 6
Final 1 2 2
TOTAL WORKLOAD (hours) 50

Contribution of Learning Outcomes to Programme Outcomes

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CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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