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Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS FIZ 6060 FREE RADICALS IN MEDICINE ELECTIVE 1 0 0 3

Offered By

Physiology

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR MÜGE KIRAY

Offered to

Physiology

Course Objective

To define of free radicals and revealing their species, sources and effects on biological systems

Learning Outcomes of the Course Unit

1   To understand about free radicals, oxidative stress and their effects on the organism 2   Can understand and analyze the research about oxidative stress 3   Comprehends the relation between free radicals with aging and diseases 4   Can use presentation technologies while sharing scientific research and literature

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description 1 Reactive oxygen species (ROS) 2 Free radicals, oxygen and nitrogen radicals 3 Metabolism and reactions that form free radicals 4 Oxidative stress 5 Lipid peroxidation 6 Oxidative DNA damage 7 Effects of free radicals on biological macromolecules 8 Midterm exam 9 Antioxidants 10 Antioxidant systems and their effect on free radicals 11 Vitamin A, Vitamin C, carotenoids 12 Diet and antioxidants 13 Relation between antioxidants with aging and diseases 14 Antioxidant and free radical measurement techniques 15 Final exam

Recomended or Required Reading

1. Free radicals in biology and medicine. Halliwel & Gutteridge, Elsevier, 2000 2. Guyton AC, Hall JE. Human Physiology. Twelfth Edition, 2011.

Planned Learning Activities and Teaching Methods

Presentation and through discussion in the form of question and answer

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA 1 PRF PERFORMANCE 2 FIN FINAL EXAM 3 FCG FINAL COURSE GRADE PRF * 0.40+ FIN* 0.60 4 RST RESIT 5 FCGR FINAL COURSE GRADE PRF * 0.40+ RST* 0.60

Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Tel: 4124478

Office Hours

Monday, 12.30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours) Lectures 14 1 14 Preparations before/after weekly lectures 14 1 14 Preparation for midterm exam 1 20 20 Preparation for final exam 1 20 20 Midterm 1 1 1 Final 1 1 1 TOTAL WORKLOAD (hours) 70

Contribution of Learning Outcomes to Programme Outcomes

PO/LO PO.1 PO.2 PO.3 PO.4 PO.5 PO.6 PO.7 PO.8 PO.9 PO.10 PO.11 PO.12 PO.13 PO.14 LO.1 5 5 5 4 4 4 3 3 3 3 3 3 3 3 LO.2 5 5 5 4 4 4 3 3 3 3 3 3 3 3 LO.3 5 5 5 5 5 5 3 3 3 3 3 3 3 3 LO.4 5 5 5 4 4 4 3 3 5 3 3 3 3 3