COURSE UNIT TITLE

: EXPERIMENTAL ANIMALS AND ADVANCED APPLICATION METHODS

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
SBE 6076 EXPERIMENTAL ANIMALS AND ADVANCED APPLICATION METHODS ELECTIVE 1 2 0 6

Offered By

The Institute Of Health Sciences

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

PROFESSOR DOCTOR OSMAN YILMAZ

Offered to

Audiology
Laboratory Animal Science
Anatomy
Molecular Pathology
Basic Oncology
Exercise Physiology
Toxicology
Physical Education and Sport Doctoral
Biochemistry
Biomechanics
Doctorate Program Rare Diseases
Histology and Embryology
Medical Biology and Genetics
Basic Oncology
Biophysics
Physiology
Musculoskeletal Tissue Engineering
Translational Oncology
Medical Parasitology
Microbiology
Pharmacology
Basic Neuroscience
Molecular Medicine
Translational Oncology
Molecular Medicine

Course Objective

By this course it is aimed to teach the students theoretically and practically information about etiology, pathogenesis of diseases; disinfection, hygiene, isolation, quarantine precautions, preventive medicine, autopsy techniques, pathological changes due to diseases,

Learning Outcomes of the Course Unit

1   LO 1. To be able to understand the biology of experimental animal
2   LO 2. To be able to assimilate basic manipulation techniques
3   LO 3. To be able to understand experimental animal selection
4   LO 4. To be able to assimilate analgesia and anesthesia in experimental animals
5   LO 5. To be able to understand scarification techniques in experimental animals
6   LO 6. To be able to understand pain control and postoperative care in animal studies
7   LO 7. To be able to apply the newly gained information in managing experimental animal studies

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Biology, anatomy, physiology, histology and biochemistry of Mouse and rat Application
2 Biology, anatomy, physiology, histology and biochemistry of rat, rabbit, guinea pig Injection techniques Application
3 Important diseases in laboratory animals Alternative methods, Sacrification techniques, autopsy techniques Application
4 Anesthesia in laboratory animals Injection techniques Application
5 Breeding and breeding techniques in laboratory animals, Basic laboratory safety and Application
6 Estrus cycles in laboratory animals Nutrition in laboratory animals Metabolism cages Application
7 Management of laboratory animal facility Occupational Health and safety Application
8 Surgical techniques in laboratory animals Life times Comparisons of human-rat and human-mouse Application
9 Steriotaksi appliance Application
10 Circadian rhythm Biostatistics, Animal models, Selection criteria of laboratory animals Application
11 MID-TERM EXAM

Recomended or Required Reading

R.Barone, C.PAVAUN, p.c. Blın, P.Cuq : Anatomıe DuLapın, Atlas Of Rabbıt Anatomy, Masson c. Editeurs 1973
Sıegfrıed Jung : Grundlagen fürdie Zucht und Haltung der wichtigsten Versuchstiere, Gustov Fıscher Verlag Stutgart 1961.
Patrick F.Sharp. Marie C.La Regina, : The Laboratory Rat, CRC Press London 1998
H.B Waynforth: Experimental and Surgical Technique in the Rat Academıc Press London 1980
James G . Fox, Bennett. J. Cohen, Franklin M. Loew : Laboratory Animal Medicine, Academıc Press, Inc. 1984.
Dr. Nail Odabaşoğlu, Prof. Dr. Ataman Güre , Yard. Doç.Dr. Eşref Yeğin , Yard. Doç.Dr. Galip Akın : Laboratuvar hayvanları I , Van 1988

Planned Learning Activities and Teaching Methods

1. Presentations
2. Topic research, interactive discussion and commenting
3. Homework preparation
4. Evaluation of information

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 ASG ASSIGNMENT
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE MTE * 0.60 +ASG * 0.10+ FIN* 0.30
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.60 +ASG * 0.10+ RST* 0.30


Further Notes About Assessment Methods

None

Assessment Criteria

1. It is evaluated if theoretical presentations were understood and if objectives were reached by midterm and final exams
2. It is evaluated if they can apply what they learned by homework presentations and discussion sessions

Language of Instruction

Turkish

Course Policies and Rules

Prerequisite: This course is a practice-oriented course. Applications start with animal handling techniques and this is the basis of all applications. For this reason, the student who will choose the course should not be afraid or disgusted by mice, rats and rabbits.

Contact Details for the Lecturer(s)

: osman.yilmaz@deu.edu.tr, 0 232 412 4651

Office Hours

Examination dates should be specified in the course content given below. The examination dates can be changed later.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 7 2 14
Practice (Reflection) 14 2 28
Preparations before/after weekly lectures 10 5 50
Preparation for midterm exam 1 9 9
Preparation for final exam 1 10 10
Preparing assignments 1 17 17
Preparing presentations 1 18 18
Preparations before/after weekly lectures 0 0 0
Final 1 2 2
Midterm 1 2 2
TOTAL WORKLOAD (hours) 150

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11PO.12PO.13PO.14PO.15PO.16PO.17
LO.14
LO.24
LO.34
LO.44
LO.54
LO.64
LO.74