COURSE UNIT TITLE

: MICROBIAL CELL IMMOBILIZATION

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
BYT 5010 MICROBIAL CELL IMMOBILIZATION ELECTIVE 3 0 0 8

Offered By

Graduate School of Natural and Applied Sciences

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR DOCTOR RAZIYE ÖZTÜRK ÜREK

Offered to

Ph.D. in Biotechnology
Ph.D. in Biotechnology
BIOTECHNOLOGY

Course Objective

Physical and chemical methods utilised in immobilization of microorganisms having many advantages compared with free cells in terms of yieldance and ease of operation, optimization criteria of immobilization conditions, some factors effecting yieldance in immobilization and applications and some applications will be discussed.

Learning Outcomes of the Course Unit

1   Have a knowledge about and discuss microorganism growth and bioproduct formation kinetic,
2   Have a knowledge about and discuss biotechnological processes, biotransformations, primer and seconder metabolite,
3   Have a knowledge and produce an idea about microbial cell immobilization methods,
4   Have a knowledge and produce an idea about fermentation technology of immobilized cells,
5   Have a knowledge and produce an idea about applications of immobilized cell in pharmaceutic and nutrient technologies.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 The Kinetics of Microorganism Growth and Bioproduct Formation, Encountered Problems
2 Biotechnological Processes
3 Biotransformations
4 Production of Primer, Seconder Metabolites
5 Microorganism Immobilization Techniques-I
6 Microorganism Immobilization Techniques-II
7 Fermentation Techniques
8 Bioreactors
9 Fermentation Applications Areas (Production of Aminoacids, Antibiotics etc.)-I
10 Fermentation Applications Areas (Production of Aminoacids, Antibiotics etc.)-II
11 Mutant Cell Immobilization
12 Applications of Immobilized Cells for Pharmaceutical Purpose
13 Applications of Immobilized Cells on Food Technology
14 Students Presentations

Recomended or Required Reading

Textbook(s): Guisan J.M. (Editor) Immobilization of Enzymes and Cells. Humana Press, 2016.
Wang D.C.J., Cooney C.L., Demain A.L., Dunnill P., Humphrey A.E. and Lilly M.D. (1988) Fermantation & Enzyme Tecnology.
Supplementary Book(s): John Willey and Sons. Weiseman A. (1980) Topics in Enzyme and Fermentation Biotechnology.
References: John Wiley, New York. Shuler, M.L., Kargi F., (1992) Bioprocess Engineering: Basic Concepts, Prentice Hall. University Press, 1995.

Planned Learning Activities and Teaching Methods

1. Presentation
2. Question-answer technique
3. Homework

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 ASG ASSIGNMENT
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE MTE *0.35 + ASG *0.25 +FIN *0.40
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) MTE *0.35 + ASG *0.25 +RST *0.40


Further Notes About Assessment Methods

None

Assessment Criteria

Meaningful learning of the basic concepts given in presentations, association of concepts with each other, establishing the cause-result relationships and making comments by using the information available for problems and evaluating idea generation are carried out with mid-term, final and resit exams, homework and presentations.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Dokuz Eylul University, Science Faculty, Chemistry Department
raziye.urek@deu.edu.tr

Office Hours

Wednesday 16.30-17.30

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 3 42
Preparation before/after weekly lectures 14 3 42
Preparing Presentations 1 30 30
Preparation for Final Exam 1 40 40
Preparation for Mid-term Exam 1 35 35
Final 1 2 2
Mid-term 1 1 1
TOTAL WORKLOAD (hours) 192

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6
LO.1544355
LO.2555455
LO.3555355
LO.4555355
LO.5555355