COURSE UNIT TITLE

: PHOTOSENSITIZER MOLECULES AND APPLICATIONS

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
KIM 6119 PHOTOSENSITIZER MOLECULES AND APPLICATIONS ELECTIVE 3 0 0 8

Offered By

Graduate School of Natural and Applied Sciences

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR DOCTOR DERYA TOPKAYA TAŞKIRAN

Offered to

Chemistry
Chemistry
Chemistry

Course Objective

The aim of this course is to introduce the design and synthesis of photosensitizers that exhibit the desired properties for various applications.

Learning Outcomes of the Course Unit

1   Ability to design photosensitizers with features designed for various applications
2   Analyze the synthesis of photosensitizers
3   To be able to obtain the opinions about photodynamic processes at molecular and mechanical levels
4   To have knowledge about the properties of photosensitizers used in different application areas such as medicine, environment and safety
5   To be able to obtain a broad knowledge of the current state of synthesis, properties and applications of photosensitizer compounds

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Definition, history and importance of photosensitizer.
2 Mechanism of photosensitizers. Electronic events of singlet oxygen production and Photosensitizers for photodynamic therapy.
3 Photosensitizers for photodynamic therapy.
4 Design and synthesis of phthalocyanines for photodynamic therapy
5 Boron-dipyromethene (BODIPY), 5-aminolevulinic acid (ALA) and phenothiazinium phototensitizers for photodynamic therapy
6 Design and synthesis of dual purpose photosensitizers for photodynamic therapy and imaging applications
7 Design and synthesis of suitable derivatives by combining photosensitizers for photodynamic therapy with nanoparticles
8 Synthesis of photosensitizers for oxidation reactions
9 Synthesis of photosensitizers for oxidation reactions (continued)
10 Use of photosensitizers for the decomposition of chemical waste causing environmental pollution
11 Use of photosensitizers for the disintegration of chemical wastes causing environmental pollution (continued)
12 Homework Presentation
13 Homework Presentation
14 Homework Presentation

Recomended or Required Reading

Textbook(s): Photosensitisers in medicine, environment, andsecurity (Springer)
Supplementary Book(s): CoordChemRev 254: 2792 2847 - Taquet J-P, Frochot C, Maneville V, Barberi-Heyob M (2007) CurrMedChem 14: 1673-1687. M. Verhille, P. Couleaud, R. Vanderesse, D. Brault, M. Barberi-Heyoband C. FrochotCurr. Med. Chem.
2010, 17, 13925-13943. Wainwright M (2004) PhotochemPhotobiolSci 3: 406 411. Wainwright M (2002) ChemSocRev 31: 128 136 - Wainwright M (2008) Anti-CancerAgents in MedicinalChemistry 8: 280-291 - GarlandMJ , Cassidy CM, Woolfson D, Donnelly RF (2009) FutureMedicinalChemistry 1: 667-691- Qian G, Wang ZY (2010)
References:
Materials: Other hazardous chemicals books, Ppt presentations which published on the internet

Planned Learning Activities and Teaching Methods

Pressentation, describing the subject, question-answer, sampling, homework

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 PRS PRESENTATION
2 ASG ASSIGNMENT
3 FCG FINAL COURSE GRADE PRS * 0.50 + ASG * 0.50


Further Notes About Assessment Methods

None

Assessment Criteria

Pressentation, describing the subject, question-answer, sampling, homework

Language of Instruction

Turkish

Course Policies and Rules

During the semester, the responsibility to continues 70% of the courses is student s self-owned. And must be observed the specified time about course times. Unethical behavior that may occur in class and on exams, will be acting within the framework of the relevant regulations. Teaching and examination implementation principles regulations of D.E.Ü Graduate School of Natural and Applied Sciences can be found at Graduate School of Natural and Applied Sciences web page.

Contact Details for the Lecturer(s)

Dokuz Eylul University, Faculty of Science, Department of Chemistry e-mail: derya.topkaya@deu.edu.tr

Office Hours

Monday, Wednesday 15.00-17.00

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 3 42
Preparations before/after weekly lectures 14 3 42
Preparation for final exam 1 55 55
Preparing assignments 4 15 60
Final 1 1 1
TOTAL WORKLOAD (hours) 200

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10PO.11
LO.13333333333
LO.22222222
LO.32222222
LO.42222222
LO.52322222

CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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