Dokuz Eylül University Information Package / Courses Catalog

Description of Individual Course Units

Course Unit Code	Course Unit Title	Type Of Course	D	U	L	ECTS
BYL 6009	NON-CODING RNAS	ELECTIVE	3	0	0	5

Offered By

Graduate School of Natural and Applied Sciences

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

ASSOCIATE PROFESSOR ERGIN ŞAHIN

Offered to

Ph.D. in Biology
Biology

Course Objective

To learn the biological functions of non-coding RNAs such as gene regulation at transcriptional and translational levels, catalytic activity and self-replication. To learn the relationship of non-coding RNAs with different diseases.

Learning Outcomes of the Course Unit

1	1. Understanding the RNA world hypothesis
2	2. To have knowledge about the different catalytic activities of RNAs
3	3. To have knowledge about self splicing catalytic RNAs
4	4. To have knowledge about the properties and functions of different, small non-coding RNAs
5	5. To have knowledge about the properties and functions of long non-coding RNAs
6	6. To learn the properties and gene regulatory functions of Riboswitches
7	7. To have knowledge about viroids and virus-like satellite RNAs

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week	Subject	Description
1	RNA World Hypothesis
2	Catalytic Properties of RNAs
3	Grup I Introns
4	Grup II Introns
5	Biological Functions of Small Interfering RNAs (siRNA)
6	Biological Functions of Micro RNAs (miRNA)
7	Biological Functions of Piwi Interacting RNAs (piRNA)
8	Biological Functions of Small Nucleolar RNAs (snoRNA)
9	Biological Functions of Small Nuclear RNAs (snRNA)
10	Biological Functions of CRISPR RNA (crRNA), Trans Activating RNA (tracrRNA) and Guide RNA ların (gRNA)
11	Biological Functions of Long Non-coding RNAs (LncRNA)
12	Riboswitches
13	Viroids and Virus-like Satellite RNAs
14	Biological Functions Of GlycoRNAs

Recomended or Required Reading

1. Walter, N., Woodson, S. A., & Batey, R. T. (Eds.). (2008). Non-protein coding RNAs (Vol. 13). Springer Science & Business Media.
2. Khalil, A. M., & Coller, J. (Eds.). (2013). Molecular biology of long non-coding RNAs. New York: Springer.
3. Yarus, M. (2010). Life from an RNA world: the ancestor within. Harvard University Press.
4. Soukup, G. A. (2013). Catalytic RNA. Academic Press.
5. Breaker, R. R. (2012). Riboswitches and the RNA world. Cold Spring Harbor perspectives in biology, 4(2), a003566.

Planned Learning Activities and Teaching Methods

The course will consist of lectures, class discussions, presentations.

Assessment Methods

SORTING NUMBER	SHORT CODE	LONG CODE	FORMULA
1	MTE	MIDTERM EXAM
2	FIN	FINAL EXAM
3	FCG	FINAL COURSE GRADE	MTE * 0.40 + FIN * 0.60
4	RST	RESIT
5	FCGR	FINAL COURSE GRADE (RESIT)	MTE * 0.40 + RST * 0.60

Further Notes About Assessment Methods

None

Assessment Criteria

mid-term and final exams

Language of Instruction

Turkish

Course Policies and Rules

Attendance to at least 70% for the lectures is an essential requirement of this course and is the responsibility of the student. It is necessary that attendance to the lecture and homework delivery must be on time. Any unethical behavior that occurs either in presentations or in exams will be dealt with as outlined in school policy. You can find the undergraduate policy at http://fbe.deu.edu.tr/

Contact Details for the Lecturer(s)

e-mail: ergin.sahin@deu.edu.tr

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities	Number	Time (hours)	Total Work Load (hours)
Lectures	14	3	42
Preparations before/after weekly lectures	14	4	56
Preparation for midterm exam	1	6	6
Preparation for final exam	1	10	10
Final	1	3	3
Midterm	1	2	2
TOTAL WORKLOAD (hours)			119

Contribution of Learning Outcomes to Programme Outcomes

PO/LO	PO.1	PO.2	PO.3	PO.5	PO.6	PO.7	PO.11	PO.12
LO.1	5	4				3	5	4
LO.2	4	4	5	4	4	3	5
LO.3	5	4	5	4	4	3	5
LO.4	4	5	5	4	4	3	5
LO.5	4	5	5	4	4	3	5
LO.6	4	5	5	4	4	3	5
LO.7	5	4	5	4	4	3	5

COURSE UNIT TITLE

DEGREE PROGRAMMES

Description of Individual Course Units

Offered By

Level of Course Unit

Course Coordinator

Offered to

Course Objective

Learning Outcomes of the Course Unit

Mode of Delivery

Prerequisites and Co-requisites

Recomended Optional Programme Components

Course Contents

Recomended or Required Reading

Planned Learning Activities and Teaching Methods

Assessment Methods

Further Notes About Assessment Methods

Assessment Criteria

Language of Instruction

Course Policies and Rules

Contact Details for the Lecturer(s)

Office Hours

Work Placement(s)

Workload Calculation

Contribution of Learning Outcomes to Programme Outcomes

CONTACT INFORMATION