COURSE UNIT TITLE

: MEDICAL BIOLOGY AND GENETICS

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
TPF 2004 MEDICAL BIOLOGY AND GENETICS COMPULSORY 2 0 0 3

Offered By

Dentist

Level of Course Unit

First Cycle Programmes (Bachelor's Degree)

Course Coordinator

PROFESSOR DOCTOR SULTAN CINGÖZ

Offered to

Dentist

Course Objective

To provide information about DNA technologies and to ensure that all this information can be used in the field of dentistry; To enable students to comprehend subjects such as human genetics, epigenetics, cell signaling, cell cycle, death, control, stem cell biology, developmental biology, population genetics; To teach the genetics factors that cause diseases ; personalise genome projects aim to inform about personalized and precision medicine.

Learning Outcomes of the Course Unit

1   Knows genetic diseases, causative factors, diagnostic methods
2   Identify, correctly hypothesize and solve problems in medical biology and genetics
3   Knows contemporary methods, techniques and tools in Medical Biology and Genetics
4   Explain the potential of DNA technologies to be used in dentistry
5   Knows the concepts of cell signaling, cell cycle, cell death and control.
6   Knows concepts such as (phenotype, genotype, Hardy-Weinberg, factors affecting gene frequency, mutation rate, migration, natural selection, genetic drift, founder effect, comparison and characterization of quantitative and qualitative traits, inbreeding) in population genetics
7   Knows the epigenetic mechanisms
8   Knows personal genome projects, personalized and precision medicine approaches
9   Knows the genetics and developmental anomalies of the oral cavity and tooth development.
10   Knows the cancer molecular mechanisms and genetics
11   Knows the stem cells and their applications in dentistry

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Cell Signaling and control
2 Biology of Cell Death (SK)
3 Epigenetic mechanisms
4 Cell cycle and its control
5 Cancer Genetics
6 Population genetics
7 Genetics of the oral cavity and tooth development
8 Genetics of the oral cavity and tooth development
9 Genetic diseases and genomic variations
10 Methods and uses in basic molecular genetics
11 Personal Genome Projects and Personalized and Precision Medicine
12 Relationship between disease and mutation (Genetics of bleeding disorders)
13 Stem Cell Biology
14 General evaluation

Recomended or Required Reading

1-Hücre, Moleküler Yaklaşım, (The Cell, A Molecular Approach 2nd edition Geoffey M. Cooper, Robert E. Hausman.) Çeviri Editörleri: Meral Sakızlı, Neşe Atabey. Izmir Tıp Kitabevi, ISBN: 9944-5148-0-2, Ankara 2006 . 2. Hücrenin Moleküler Biyolojisi, (Molecular Biology of the Cell,4th Edition. Ed. Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter. Garland Publishers) Çeviri Editörleri: Nur Buyru, Nejat Dalay, Meral Özgüç, Mehmet Öztürk, Meral Sakızlı, ISBN: 978-9944-252-22-5, TÜBA ders kitapları, 2008 3. Thompson & Thompson Tıbbi Genetik - Mehmet Alikaşifoğlu, Güneş Tıp Kitabevleri. 4.Yaşam( LIFE: The Science of Biology, Ninth Edition. David Sadava, David M. Hills, H. Craig Heller, MayR. Berenbaum) Çeviri Editörleri: prof. Ertunç Gündüz, Prof. Dr. Ismail Türkan. 5.Neil A. Campbell and Jane A. Reece Çeviri Editörleri: Prof. Dr. Ertunç Gündüz, Prof. Dr. Ali Demirsoy, Ismail Türkan. 2008, Palme Yayıncılık.

Planned Learning Activities and Teaching Methods

Lectures will be made by using projector, computer, animation etc face-to-face. Student participation will be provided in the form of questions and answers.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1
2 FN Final
3 FSB Final Sonu Başarı Notu
4 BUT Bütünleme
5 BSB Bütünleme Sonu Başarı Notu


Further Notes About Assessment Methods

None

Assessment Criteria

1.Will be evaluated as criteria the accuracy of the answers given to the questions asked in the written midterm and final exam

2. Midterm exam success rate 60%
3.Final success rate 40%
3. Attendance and in-class participation are evaluation as criteria.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Phone: 0232 412 4604 E-mail: sultan.cingoz@deu.edu.tr

Office Hours

Mondays: 15:10 -16:50

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 2 28
Preparations before/after weekly lectures 12 3 36
Preparation for midterm exam 1 5 5
Preparation for final exam 1 5 5
Midterm 1 2 2
Final 1 2 2
TOTAL WORKLOAD (hours) 78

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10
LO.133
LO.233
LO.334
LO.434
LO.533
LO.633
LO.733
LO.834
LO.933
LO.1034
LO.1134