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Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS TPF 1003 BIOCHEMISTRY COMPULSORY 2 0 0 4

Offered By

Dentist

Level of Course Unit

First Cycle Programmes (Bachelor's Degree)

Course Coordinator

PROFESSOR DOCTOR EMEL ALTEKIN

Offered to

Dentist

Course Objective

The aim of the course is to enable the students to learn the structures and functions of biomolecules which are the building blocks of living organisms, and to comprehend the functioning and regulation of human metabolism.

Learning Outcomes of the Course Unit

1   To understand the molecular basics of life and chemical properties of biomolecules 2   To be able to define the structure and properties and to classify the biomolecules (carbohydrates, lipids, amino acids, proteins, nucleic acids) 3   To be able to define and classify enzymes, to understand the regulation of enzyme activity 4   To understand the metabolism of biomolecules and the interrelationship of biochemical pathways 5   To correlate the metabolism of biomolecules with diseases 6   To understand the integration and regulation of metabolism 7   To understand the basic concepts of nutrition 8   To understand the importance and role of vitamins, macro and micro elements in the metabolism 9   To be able to define and classify hormones, to understand their metabolism and correlate hormones with diseases

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description 1 Presentation week 2 The molecular basis of life 3 pH and buffer systems 4 Cell, subcellular organelles , membranes and transport 5 Biomolecules, Molecular orbitals and interactions between molecules 6 Compounds with functional groups, aromatic and polycyclic hydrocarbons 7 Stereoisomeric properties of biomolecules 8 Amino Acids; structure, classification, reactions and transport /Peptides and proteins; structural properties 9 Protein Biosynthesis and Posttranslational Modifications 10 Enzymes: Structure, classification, enzyme kinetics Regulation of enzyme activity 11 Carbohydrates and Lipids; Structure and classification 12 Nutrition: Basic concepts and nutrients 13 Vitamins and cofactors 14 Macro ve microelements 15 Metabolism: Introduction and basic concepts/Bioenerjetics; oxidative phosphorilation, electron transport and mitochondria 16 Glycolysis, Gluconeogenesis, Regulation of glycolysis and production of energy/Citric acid cycle and regulation 17 Hexose mono phosphate shunt, Fructose and Galactose / Glycogenesis ve Glycogenolysis 18 Lipid metabolism (Fatty acids, acylglycerols ve sphingolids) 19 The metabolism of cholesterol and its derivatives / Lipoproteins and Atherosclerosis 20 Metabolism of amino acids: Catabolism of carbon skeletons, disposal of nitrogen and urea cycle 21 The integration of metabolism, biochemistry of starvation and fed state 22 Compouns derived from amino acids/Nucleotides 23 Heme; synthesis and catabolism /Hemoglobin 24 Detoxification , Alcohol met. 25 Oxygen radicals 26 Hormones; classification, mechahisms of action,signal transduction /Hormones of hypothalamus, hypophysis, pineal gland and gonads ; Structure and metabolism 27 Hormones of gonads and adrenal gland ; Structure and metabolism 28 Hormones of thyroid /GIT and pancreas/Lipid tisuue; Structure and metabolism

Recomended or Required Reading

To be announced.

Planned Learning Activities and Teaching Methods

Theoretical lecture Interactive lecture

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA 1 VZ1 1.Vize 2 VZ2 2.Vize 3 VOR Vize Ortalaması roundVZ1 * 0.50 + VZ2 * 0.50,0 4 FN Final 5 FSB Final Sonu Başarı Notu roundVOR * 0.40 + FN * 0.60,0 6 BUT Bütünleme 7 BSB Bütünleme Sonu Başarı Notu roundVOR * 0.40 + BUT * 0.60,0

Further Notes About Assessment Methods

None

Assessment Criteria

To be announced.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Professor Emel Altekin MD. Dokuz Eylül University Medical Faculty Department of Medical Biochemistry IZMIR Tel: 232-412 4412 Gsm: 05335460609

Office Hours

Monday 09:30-11:30 AM

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours) Lectures 26 2 52 Preparation for final exam 1 35 35 Preparation for midterm exam 2 10 20 Final 1 2 2 Midterm 2 1 2 TOTAL WORKLOAD (hours) 111

Contribution of Learning Outcomes to Programme Outcomes

PO/LO PO.1 PO.2 PO.3 PO.4 PO.5 PO.6 PO.7 PO.8 PO.9 PO.10 LO.1 3 3 LO.2 3 4 LO.3 3 4 LO.4 3 4 LO.5 3 4 LO.6 3 4 LO.7 3 5 LO.8 3 4 LO.9 3 4