COURSE UNIT TITLE

: SMALL ANIMAL MODELS FOR BIOMEDICAL RESEARCH

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
BST 5015 SMALL ANIMAL MODELS FOR BIOMEDICAL RESEARCH ELECTIVE 3 0 0 9

Offered By

Biomedicine and Health Technologies

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

ASSISTANT PROFESSOR GÜLÇIN ÇAKAN AKDOĞAN

Offered to

Biomedicine and Health Technologies

Course Objective

To obtain basic information about commonly used laboratory animals and their areas of use in biomedicine research. To compare models to make an informed choice when choosing a model. To learn basics approaches for developing genetically modified animals.

Learning Outcomes of the Course Unit

1   Learning small laboratory animals and their areas of use
2   Learning international and national ethical regulations
3   Learning the creation and characteristics of transgenic and mutant animals
4   Learning most widely used small vertebrate and invertebrate models
5   ning basics of disease modeling approaches with laboratory animals

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Brief History of lab animals: Rodents , Zebrafish, Xenopus and fruit fly
2 Animal experimentation ethics guidelines
3 Rodents
4 Small Vertebrates: fish species and the frog
5 Invertebrates: Fruit fly, worms
6 Comparative anatomy of animals and humans
7 MidTerm Exam
8 Comparative Genome of animals and humans
9 Production and use of transgenic and mutant animals
10 Production of gene knockout and knock-in animal models
11 Comparative imaging techniques for animal models
12 Disease models
13 Animal models of digestive system diseases
14 Animal models of rare diseases
15 Project presentations
16 Final Exam

Recomended or Required Reading

To be announced.

Planned Learning Activities and Teaching Methods

Theoretical lectures with literature review/discussion, applied computer practical, student presentations

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 ASG ASSIGNMENT
2 MTE MIDTERM EXAM
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE ASG * 0.30 + MTE * 0.30 + FIN * 0.40
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) ASG * 0.30 + MTE * 0.30 + RST * 0.40


Further Notes About Assessment Methods

Mid-term exam %20
Quiz %10
Homework Assignments %10
Project presentation %15
Active participation to the lecture %5
Final Exam %40

Assessment Criteria

Project presentation: Each student will define a problem and design a project that utilizes techniques in the course syllabus and deliver a 10 min presentation.

Language of Instruction

English

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

gulcin.cakan@deu.edu.tr

Office Hours

1 hr weekly. Day and time TBA.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 3 42
Preparations before/after weekly lectures 14 5 70
Preparation for midterm exam 1 16 16
Preparation for final exam 1 20 20
Preparing assignments 2 12 24
Project Preparation 1 30 30
Midterm 1 2 2
Quiz etc. 4 0,5 4
Final 1 5 5
TOTAL WORKLOAD (hours) 213

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8
LO.144324
LO.22445
LO.35453453
LO.445545
LO.554354