COURSE UNIT TITLE

: ADVANCED RESEARCH TECHNIQUES IN MOLECULAR MEDICINE

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
BST 6022 ADVANCED RESEARCH TECHNIQUES IN MOLECULAR MEDICINE ELECTIVE 3 0 0 12

Offered By

Biomedicine and Health Technologies

Level of Course Unit

Third Cycle Programmes (Doctorate Degree)

Course Coordinator

ASSISTANT PROFESSOR GÜLÇIN ÇAKAN AKDOĞAN

Offered to

Biomedicine and Health Technologies

Course Objective

Learning advanced gene and protein analysis methods used in in vitro and in vivo biomedicine research. Learning the rules and methods of imaging and image analysis. Learning the applications of interdisciplinary research approaches through literature review.

Learning Outcomes of the Course Unit

1   Learning space-time dependent gene expression analysis methods
2   Learning space-time dependent protein expression analysis methods
3   Learning optical imaging principles and image processing
4   Learning data reporting rules
5   Being able to define biological questions and test hypothesis
6   Being able to analyze correct applications from literature

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Interdisciplinary research approach in molecular medicine
2 Spatiotemporal analysis of gene expression - I quantitative PCR primer design and data analysis
3 Spatiotemporal analysis of gene expression- II in situ hybridisation
4 Spatiotemporal analysis of gene expression- III Transcriptomics
5 Spatiotemporal analysis of protein expression - I IF, IHC, and western blot
6 MidTERM
7 Spatiotemporal analysis of protein expression - II Proteomics
8 Research Project Design
9 Optical imaging
10 Image processing with FIJI - I
11 Image processing with FIJI - II
12 Essentials of data reporting - I
13 Essentials of data reporting - II
14 Examples of applied research - I
15 Examples of applied research - II
16 FINAL EXAM

Recomended or Required Reading

To be announced.

Planned Learning Activities and Teaching Methods

Theoretical PowerPoint lectures with literature review/discussion, applied computer practicals.

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 ASG ASSIGNMENT
2 MTE MIDTERM EXAM
3 FIN FINAL EXAM
4 FCG FINAL COURSE GRADE ASG * 0.30 + MTE * 0.30 + FIN * 0.40
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) ASG * 0.30 + MTE * 0.30 + RST * 0.40


Further Notes About Assessment Methods

Mid-term exam %20
Quiz %10
Homework Assignments %10
Project presentation %15
Active participation to the lecture %5
Final Exam %40

Assessment Criteria

Project presentation: Each student will define a problem and design a project that utilizes techniques in the course syllabus, conduct analyses and deliver a 10 min presentation.

Language of Instruction

English

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

gulcin.cakan-at-deu.edu.tr

Office Hours

1hr weekly, day and time TBA

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 3 42
Preparations before/after weekly lectures 14 6 84
Preparation for midterm exam 1 20 20
Preparation for final exam 1 30 30
Preparing assignments 4 13 52
Preparing presentations 2 25 50
Midterm 1 3 3
Quiz etc. 4 0,5 4
Final 1 5 5
TOTAL WORKLOAD (hours) 290

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8
LO.15542
LO.253352
LO.3334444
LO.443543
LO.544342
LO.64444