COURSE UNIT TITLE

: PHARMACEUTICAL CHEMISTRY AND ANALYSES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
KMT 4226 PHARMACEUTICAL CHEMISTRY AND ANALYSES ELECTIVE 2 0 0 2

Offered By

Chemistry Technology

Level of Course Unit

Short Cycle Programmes (Associate's Degree)

Course Coordinator

ASSOCIATE PROFESSOR MERVE ZEYREK

Offered to

Chemistry Technology

Course Objective

The aim of this course is to provide basic information about the definition, classification, production techniques and analysis of the drug.

Learning Outcomes of the Course Unit

1   To be able to define basic concepts related to drug and pharmaceutical chemistry.
2   To be able to classify drugs according to their sources.
3   To be able to sort the production methods used in the pharmaceutical industry.
4   To be able to sort titrimetric analyses applied to drugs.
5   To be able to sort instrumental analyses applied to drugs

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Drug definition, naming and classification of drugs
2 Forms of use of drugs, solid, liquid, semi-solid and other pharmaceutical forms
3 Classification of production technologies in the pharmaceutical industry
4 Sterilization in pharmaceutical production, sterile drug production
5 Tablet drug production and control tests
6 Tablet drug production and control tests
7 Good manufacturing practices (GMP) in the pharmaceutical industry
8 Mid-Term Exam
9 Drug analysis methods, classification and identification of methods
10 Introduction to titrimetric analysis, titrimetric analysis applications (Acidimetry and Alkalimetry), quantity determination of quinine hydrochloride, quantity determination of acetylsalicylic acid (aspirin).
11 Applications of titrimetric analysis, (Iodometry, Nitritometry, Permanganometry) quantity determination of antipyrine (phenazone), quantity determination of sulfoguanidine, quantity determination of calcium lactate.
12 Introduction to pharmacopoeia analysis, pharmacopoeia analysis applications, acetylsalicylic acid tablet analysis, ascorbic acid analysis
13 Pharmacopoeia analysis applications, sulfadimidine tablet analysis, citric acid analysis
14 Introduction to instrumental analysis methods, quantity determination of drug active substances in the visible region by spectroscopic method (UV-Visible), paracetamol analysis
15 Purity control and quantity determination of drug active substances by chromatographic methods (HPLC and GC-MS), ibuprofen analysis

Recomended or Required Reading

Textbooks/References/Materials:
Textbook:

1. Ilaç Kimyasına Giriş, Graham L. Patrick, Çeviri Editörü:Vildan Adar Gürsoy, Bilim Yayınları, 2018.
2. Ilaç: Tasarım, Sentez ve Analiz Yöntemleri, Selma Saraç, S. Ebru Büyüktuncel, Arzu Karakurt, Ankara Nobel Tıp Kitabevleri, 2024.

Supplementary Book(s):

Ilaç Kimyasına Giriş, Nurettin Mengeş, Gece Kitaplığı, 2020.

Planned Learning Activities and Teaching Methods

1. Lecture
2. Question-Answer

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 FN Final
3 FCG FINAL COURSE GRADE VZ*0.40 + FN* 0.60
4 RST RESIT
5 FCGR FINAL COURSE GRADE (RESIT) VZ*0.40 + BUT* 0.60


Further Notes About Assessment Methods

None

Assessment Criteria

The five learning outcomes will be assessed by mid-term and final exams.

Language of Instruction

Turkish

Course Policies and Rules

1. The students have to attend 70% of the courses.
2. Any act of cheating will be resulted in disciplinary investigation.

Contact Details for the Lecturer(s)

0232 - 3012613
suat.ucar@deu.edu.tr
merve.zeyrek@deu.edu.tr
muge.hatip@deu.edu.tr

Office Hours

The appropriate office hours will be announced to the students at the beginning of the term.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 2 28
Preparations before/after weekly lectures 14 1 14
Preparation for midterm exam 1 4 4
Preparation for final exam 1 8 8
Midterm 1 1 1
Final 1 1 1
TOTAL WORKLOAD (hours) 56

Contribution of Learning Outcomes to Programme Outcomes

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