COURSE UNIT TITLE

: PATHOPHYSIOLOGY APPROACHES I

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
HEM 5095 PATHOPHYSIOLOGY APPROACHES I ELECTIVE 2 0 0 6

Offered By

Department of Nursing

Level of Course Unit

Second Cycle Programmes (Master's Degree)

Course Coordinator

PROFESSOR DOCTOR ÖZLEM BILIK

Offered to

Internal Medicine Nursing
Oncology Nursing
COMMUNITY HEALTH NURSING
Obstetrics and Gynaecology Nursing
Pediatric Nursing
Surgical Nursing
Psychiatric Nursing
Emergency and Clinical Care Nursing
Fundamentals of Nursing
OCCUPATIONAL HEALTH NURSING

Course Objective

This course aims to teach the student basic physiopathological subjects and concepts. In this course It is focused on thephysiopathologies of the most frequent diseases disordering the cell, organ, system functions. Students are taught about the basic physiopathological mechanisms which forms at the cell level. Students discuss on the organ and system function disorders and the symptoms presented with case examples by asking cause-effect questions. Students gain the ability in questioning the physiopathological changes in clinical situations and analyzing them by using his/her factual/conceptual learning he/she has had.

Learning Outcomes of the Course Unit

1   The students identifies normal cell organ and system functions.
2   The student explains the physiopathological mechanisms which are formed in cell organ and system functions.
3   The student shows the physiopathological process of the clinical symptoms given in the case examples
4   The student analyzes the physiopathology of the problems in clinical situations he/she meets.
5   The student assesses the results of the symptoms/diagnosis/laboratory and the related physiopathological mechanisms.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Cell Biology: Its structure and function, cell organalles, cell-cell adhesion, cell-to-cell communication, cell metabolism, membrane transport, cellular products, multiplication and tissue formation Prof. Fatma Vural
2 Changes in Cell and Tissue Biology: Cellular adaptation, cell injurying and its symptoms, necrosis, cell in old age and changes in tissue Prof. Fatma Vural
3 Changes in cell and tissue biology: Cellular adaptation, cell injury, manifestations of cell injury, cell death, changes in cells and tissues during aging Prof. Fatma Vural
4 Inflammation: Defense mechanisms; physical, biological, and chemical barriers; inflammation, vascular, cellular response, plasma protein system Assoc. Prof. Aklime Sarıkaya
5 Continued Inflammation Cellular products, local and systemic signs of inflammation; fever, leukocytosis, plasma protein synthesis, chronic inflammation, repair; reconstructive, maturational, and dysfunctional wound healing; characteristics of self-defense mechanisms in children and the elderly Assoc. Prof. Aklime Sarıkaya
6 General Pathology of Infectious Diseases: Epidemic infectious diseases; classification of infectious agents and the body's barriers and their breakdown, disease-causing mechanisms of infectious agents, characteristics of the inflammatory response to infectious agents. Prof. Özlem Bilik
7 Continue - Infectious Diseases Microorganisms' immune system bypass, survival mechanisms, special diagnostic techniques and clinical manifestations of infectious diseases, vaccines, and the effects of antimicrobial agents. Prof. Özlem Bilik
8 Midterm Prof. Özlem Bilik
9 Central nervous system: Evaluation of consciousness, pupillary, motor, sensory, speech, respiratory, cardiac autonomic responses Prof. Özlem Küçükgüçlü
10 Central nervous system: Continued Multiple Sclerosis, Myasthenia Gravis, Meningitis, Amyotrophic Lateral Sclerosis, Dementia, Parkinson's Prof. Özlem Küçükgüçlü
11 Central nervous system: Impairment of consciousness; KIBA syndrome, CVO, trauma-related epidural hematoma and subdural hematoma, aneurysms and malformations, herniations, hydrocephalus Prof. Fatma Vural
12 Immunity General characteristics, humoral and cellular immunity, active and passive immunity, immune structure and response, antigen, immunogen, antigen-presenting molecules and cytokines and their receptors, maturation of T and B cells or columnar change, induction of immune response, function of T lymphocytes and immunoglobulins, immune function in fetal, neonatal, and elderly age Prof. Özlem Bilik
13 Alterations in the Immune Response Hypersensitivity, allergy, autoimmunity, allo-unit, immune deficits; primary, secondary deficits, clinical presentation, and treatment approaches Prof. Özlem Bilik
14 Endocrine system and diseases Diabetes Mellitus - Hyperglycemia, Hypoglycemia; Thyroid Diseases - Hypothyroidism, Hyperthyroidism, Thyroid crisis; Adrenal Diseases - Cushing's Syndrome, Addison's Disease Prof. Hatice Mert
15 Endokrin sistem ve hastalıkları- Devam Prof. Hatice Mert

Recomended or Required Reading

McCance KL, Huether SE. (2005). Pathophysiology The Biologic Basis For Disease in Adults and Children, The C.V. Mosby Company, StLouis,.
3. Çevikbaş U (Çev. Ed). (2002). Temel Patoloji, Kumar V, Cortran RS., Robbins SL. Basic Pathology., Yüce Yayınları A.Ş, Istanbul.
1. Porth MC. (1998). Pathophysiolog Concepts of Altered Health States, 5th Ed., Lippincott Comp., Philadelphia,.
4. Guyton CA, Hall J. (1996). Tıbbi Fizyoloj,i Çev: Hayrunisa Çavuşoğlu, 10th. Ed., W.B. Saunders Comp., Philadelphia.
5. Kumar V, Abbas A, Fousta N, Mitchell R. Robbins (2008). Basic Pathology, 8th Ed., Saunders Book Company, Philadelphia.
6. Carrier-Kohlman V. (2003). Pathophysiological Phenomena in Nursing: Human Responses to Illness, 2nd ed., WB Saunders Company, Philadelphia.

Planned Learning Activities and Teaching Methods

Visually supported presentation
Questions-Answers
Group discussion
Brainstorming
Case discussion
Video/Animations

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 ASG ASSIGNMENT
3 PAR PARTICIPATION
4 FCGR FINAL COURSE GRADE (RESIT) VZ*0.20+ODV*0.25+DKL*0.25+FN*0.30
5 RST RESIT
6
7


Further Notes About Assessment Methods

Each student will prepare a written report in APA format, explaining 2-3 discussion questions assigned in each section throughout the semester based on current literature, and submit it to the relevant faculty member online or in writing.
Assignments are expected to include:
The assignment cover page must include the Institute, Department, Course Code, Name, Student's name, surname, and number, the name and surname of the instructor, the assignment due date, and the page number.
Students are expected to explain each question in these 2-3 analytical questions using knowledge acquired from at least one primary book, one Turkish and one English research article. They may use more if desired.
The answers to the questions must address the questions "What ", "Why ", "Where ", "When ", "How ", and "How much " related to the relevant topic.
Assignments must be written in APA format.
Diagrams and images may be used, citing their sources according to APA format.
The assignment, including the cover page and reference page, must not exceed four pages.
It must include a student self-assessment.

Assessment Criteria

Which aspects of learning outcomes are assessed by which assessment criteria Assessment criterias must be associated to the learning methods.)

LO1-4 Midterm,Final;
LO1-5 Presentation, attendance to the course
LO4-5 Written homeworks answering the short discussion questions

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Prof. Özlem Küçükgüçlü ozlem.kguclu@deu.edu.tr Phone: 0 232 412 6966
Prof. Hatice Mert hatice.mert@deu.edu.tr Phone: 0 232 4124786
Prof. Özlem Bilik ozlembilik71@gmail.com Phone: 0 232 412 6962
Prof. Fatma Vural fatma.vural@deu.edu.tr Phone:0 232 4124780
Assoc. Prof. Aklime Sarıkaya aklime.sarikaya@deu.edu.tr Phone: 0232 412 4788

Office Hours

To be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 2 28
Preparations before/after weekly lectures 13 2 26
Preparation for midterm exam 1 26 26
Preparation for final exam 1 28 28
Preparing assignments 2 10 20
making presentation 1 20 20
Final 1 2 2
TOTAL WORKLOAD (hours) 150

Contribution of Learning Outcomes to Programme Outcomes

PO/LOPO.1PO.2PO.3PO.4PO.5PO.6PO.7PO.8PO.9PO.10
LO.1555
LO.2555
LO.3555
LO.4555
LO.5555