COURSE UNIT TITLE

: CHEMICALS AND TOXICOLOGY

DEGREE PROGRAMMES

Description of Individual Course Units

Course Unit Code Course Unit Title Type Of Course D U L ECTS
KIM 1113 CHEMICALS AND TOXICOLOGY ELECTIVE 2 0 0 3

Offered By

Chemistry

Level of Course Unit

First Cycle Programmes (Bachelor's Degree)

Course Coordinator

ASSOCIATE PROFESSOR CATALINA NATALIA YILMAZ

Offered to

Chemistry

Course Objective

The aim of this course is to provide students with a comprehensive understanding of how chemicals interact with the human body, including absorption, cellular effects, and biotransformation. Students will learn about the mechanisms of chemical toxicity, dose response relationships, toxicity testing, and risk assessment. The course also covers preventive measures and examines chemicals that pose specific health risks, such as carcinogens, embryotoxic, allergenic, and environmental toxicants. By the end of the course, students are expected to critically analyze and apply this knowledge to evaluate chemical hazards and promote safety in health and environmental contexts.

Learning Outcomes of the Course Unit

1   Evaluate the transport ways of chemicals to the body besides effects and biotransformation of the chemicals into cell,
2   Comprehend and have information on toxic and adverse effects mechanisms of some chemicals in metabolism
3   Discuss the effect doses of some chemicals and protection ways,
4   Have knowledge on chemicals that cause to cancer and their effect mechanisms,
5   Explain and state toxic chemicals to embryo; chemicals that lead allergy and health risk.

Mode of Delivery

Face -to- Face

Prerequisites and Co-requisites

None

Recomended Optional Programme Components

None

Course Contents

Week Subject Description
1 Introduction to Toxicology and Fundamental Concepts
2 Absorption of Chemicals into the Body
3 Elimination and Biotransformation of Chemicals
4 Cellular Effects and Metabolism of Chemicals - Part I
5 Cellular Effects and Metabolism of Chemicals - Part II
6 Toxic Mechanisms of Selected Chemicals - Part I (Oxidative stress, free radicals)
7 Toxic Mechanisms of Selected Chemicals - Part II (Mitochondrial toxicity, neurotoxicity)
8 Dose- Response Relationships and Effect Levels
9 Toxicity Testing
10 Risk Assessment
11 Ways to Prevent Toxic Effects
12 Carcinogenic Chemicals Part I (Classification, general mechanisms)
13 Health Risk of Chemicals (Allergens, endocrine disruptors, environmental toxicants) and Special Toxic Effects
14 Student Presentations and General Review

Recomended or Required Reading

Casarett & Doull s Toxicology: The Basic Science of Poisons

Hayes Principles and Methods of Toxicology

Klaassen, C. D. Casarett & Doull s Essentials of Toxicology
Latest articles, reports and lecture notes

Planned Learning Activities and Teaching Methods

Presentation, Question-answer technique, Application, Homework

Assessment Methods

SORTING NUMBER SHORT CODE LONG CODE FORMULA
1 MTE MIDTERM EXAM
2 ASG ASSIGNMENT
3 FIN FINAL EXAM
4 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.40 + ASG * 0.20 + FIN * 0.40
5 RST RESIT
6 FCGR FINAL COURSE GRADE (RESIT) MTE * 0.40 + ASG * 0.20 + RST * 0.40


Further Notes About Assessment Methods

None

Assessment Criteria

Meaningful learning of the basic concepts given in presentations, association of concepts with each other, establishing the cause-result relationships and making comments by using the information available for problems and evaluating idea generation are carried out with mid-term and final exams, active participation to the lecture, homework.

Language of Instruction

Turkish

Course Policies and Rules

To be announced.

Contact Details for the Lecturer(s)

Doç Dr. Catalina Natalia YILMAZ
Dokuz Eylul University, Faculty of Science, Department of Chemistry (Ofice A352/1)
Email: catalinanatalia.yilmaz@deu.edu.tr

Office Hours

It will be announced.

Work Placement(s)

None

Workload Calculation

Activities Number Time (hours) Total Work Load (hours)
Lectures 14 2 28
Preparations before/after weekly lectures 14 1 14
Preparation for midterm exam 1 10 10
Preparation for final exam 1 20 20
Preparing assignments 1 7 7
Final 1 2 2
Midterm 1 2 2
TOTAL WORKLOAD (hours) 83

Contribution of Learning Outcomes to Programme Outcomes

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CONTACT INFORMATION
Dokuz Eylül Üniversitesi Cumhuriyet Bulvarı No: 144 35210 Alsancak / İZMİR
Phone: +90(232) 412 12 12 - Fax: +90 (232) 464 81 35

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