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DOÇ.DR. ŞERİF ŞENTÜRK İZMİR ULUSLARARASI BİYOTIP VE GENOM ENSTİTÜSÜ GENOM BİLİMLERİ VE MOLEKÜLER BİYOTEKNOLOJİ ANABİLİM DALI

  • Eğitim / Akademik Bilgisi
    Lisans  Boğaziçi Üniversitesi Fen - Edebiyat Fakültesi Moleküler Biyoloji ve Genetik  2003
    Doktora  İ. D. Bilkent Üniversitesi Enstitü Moleküler Biyoloji ve Genetik Dalı  2010
    Yardımcı Doçent  Dokuz Eylül Üniversitesi İzmir Uluslararası Biyotıp ve Genom Enstitüsü  2015
    Doçent  Üniversitelerarası Kurul Başkanlığı Moleküler Biyoloji ve Genetik  2017
  • NO AD YIL
    1  AXL Knock-Out in SNU475 Hepatocellular Carcinoma Cells Provides Evidence for Lethal Effect Associate...  2021
    2  Changes in Wnt and TGF-ß Signaling Mediate the Development of Regorafenib Resistance in Hepatocellul...  2021
    3  Systematic Analysis of Cytostatic TGF-Beta Response in Mesenchymal-Like Hepatocellular Carcinoma Cel...  2021
    4  An epigenetic switch regulates the ontogeny of AXL positive/EGFR-TKI resistant cells by modulating m...  2021
    5  Recruitment of solid lipid nanoparticles for the delivery of CRISPR/Cas9: primary evaluation of anti...  2021
    6  Retinoic acid signaling and bladder cancer: Epigenetic deregulation, therapy and beyond...  2021
    7  Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)...  2021
    8  The Jekyll and Hyde of Cellular Senescence in Cancer...  2021
    9  Genomics and Functional Genomics of Malignant Pleural Mesothelioma...  2020
    10  Next-Generation Liver Medicine Using Organoid Models...  2019
    11  Thioredoxin interacting protein promotes invasion in hepatocellular carcinoma...  2018
    12  Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization...  2017
    13  TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functi...  2016
    14  A rapid and tunable method to temporally control Cas9 expression enables the identification of essen...  2015
    15  MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppressio...  2015
    16  p53psi is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like ...  2014
    17  Imetelstat (a telomerase antagonist) exerts off target effects on the cytoskeleton...  2013
    18  Inhibition of Akt signaling in hepatoma cells induces apoptotic cell death independent of Akt activa...  2011
    19  Dose- and time-dependent expression patterns of zebrafish orthologs of selected E2F target genes in ...  2011
    20  Transforming growth factor-beta induces senescence in hepatocellular carcinoma cells and inhibits tu...  2010
    21  The ability to generate senescent progeny as a mechanism underlying breast cancer cell heterogeneity...  2010
    22  Senescence and immortality in hepatocellular carcinoma...  2009
    23  Canonical Wnt signaling is antagonized by noncanonical Wnt5a in hepatocellular carcinoma cells...  2009
    24  Reprogramming of replicative senescence in hepatocellular carcinoma-derived cells...  2006
  • NO AD TARİH
    1  Küçük Hücreli Dışı Akciğer Kanserinde Genetik Olmayan Osimertinib Direnç Mekanizmalarının... 28/10/2021 - 31/10/2021
    2  Generation of R132H point mutation by CRISPR/Cas9 method in colon cancer cell line... 16/09/2021 - 18/09/2021
    3  Generation of cell models using CRISPR/Cas9-based gene therapy to study molecular functions of IDH i... 09/09/2021 - 11/09/2021
    4  Revealing the Role of Retinoids On the Phenotypic and Epigenetic Landscape of Bladder Cancer Cells... 10/04/2021 - 11/04/2021
    5  Identification of Essential Genes in Malignant Pleural Mesothelioma Using Genome-Wide CRISPR/Cas9-Ba... 28/01/2021 - 31/01/2021
    6  Gen Düzeltme ve CRISPR... 15/10/2020 - 18/10/2020
    7  Genom Düzenlemede Genç Araştırmacılar İçin Fırsatlar... 05/03/2020 - 07/03/2020
    8  A Novel Concept for Immune Checkpoint Gene Knockout Via Lipid Based Non-Viral Delivery Systems... 05/03/2020 - 07/03/2020
    9  CRISPR-Cas9 Genom Düzenleme... 26/02/2020 - 28/02/2020
    10  Malign plevral mezotelyoma tümörigenez mekanizmalarının CRISPR-Cas9 tarama ile araştırılması... 14/11/2019 - 17/11/2019
    11  Hepatoselüler karsinom hücre hatlarında Malt1 tükenmesinin büyüme baskılayıcı etkilerinin a... 14/11/2019 - 17/11/2019
    12  Hepatoselüler karsinomda TGF-ß yanıtının hücresel mekanizmalarının araştırılması... 14/11/2019 - 17/11/2019
    13  TGF-beta'ya bağlı kanser hücre sekretomunun regülasyonunda Malt1'ın rolü... 14/11/2019 - 17/11/2019
    14  İnvaziv olan ve invaziv olmayan mesane kanseri hücre hatlarını karakterize eden transkripsiyonel... 14/11/2019 - 17/11/2019
    15  Hepatoselüler karsinomda AXL'ın rolü... 14/11/2019 - 17/11/2019
    16  Genome-wide CRISPR-Cas9 Screening for Identification of Cancer Essential Genes in Malign Pleural Mes... 27/10/2019 - 31/10/2019
    17  HEPATOSELÜLER KARSİNOMADA YENİ YAKLAŞIM: POTANSİYEL İLAÇ HEDEFİ OLARAK AXL RESEPTÖRÜ... 14/10/2019 - 17/10/2019
    18  Identification of transcriptional regulatory networks characterizing invasive and non-invasive bladd... 03/10/2019 - 05/10/2019
    19  Malt1 Paracaspase Inhibition Reduces Hepatocellular Carcinoma Cell Survival... 18/09/2019 - 22/09/2019
    20  Malt1 Parakaspazın Hepatoselüler Karsinom Hücre Sağkalımı Üzerindeki Rolünün Araştırılma... 21/02/2019 - 23/02/2019
    21  Hepatoselüler Karsinom'da TGF-beta Direncinin Hücresel Mekanizmalarının Araştırılması... 21/02/2019 - 23/02/2019
    22  Kanser Esansiyel Genlerin Tüm Genom CRISPR-Cas9 Taramalarla Araştırılması... 18/10/2018 - 21/10/2018
    23  AXL as a Potential Target in Liver Cancer... 05/09/2018 - 08/09/2018
    24  Engineering and Functional Validation of Clonal Cell Lines with Stable Cas9 Expression for Genome-Wi... 05/09/2018 - 08/09/2018
    25  The Role of Malt1 Paracaspase in Hepatocellular Carcinoma... 05/09/2018 - 08/09/2018
    26  Investigation of the Cellular Mechanisms of TGF-beta-induced Senescence-Resistance in Hepatocellular... 05/09/2018 - 08/09/2018
    27  Systematic Comparison of Constitutive Promoters in Chinese Hamster Ovary Cells... 05/09/2018 - 08/09/2018
    28  The New Frontier of Genome Engineering: The CRISPR-Cas9 System ... 24/05/2018 - 27/05/2018
    29  Genom Mühendisliği ve CRISPR-Cas Devrimi... 10/05/2018 - 13/05/2018
    30  Biomarkers and CRISPR... 10/05/2017 - 12/05/2017
    31  CRISPR-Cas9 İşlevsel Genomik Tarama ve Rekabet Tayini ile Kanser Esansiyel Genlerin Keşfi ve İn ... 10/02/2017 - 12/02/2017
    32  Truncating Alleles in TP53 Produce Separation of Function Mutants That Actively Promote Tumorigenesi... 01/06/2016 - 05/06/2016
    33  In Vitro and In Vivo Characterization Of Cell Survival Genes Using Destabilized Cas9... 04/05/2016 - 07/05/2016
    34  A rapid and tunable method to temporally control Cas9 expression enables the characterization of ess... 24/09/2015 - 27/09/2015
    35  Does Akt inactivation promote metastasis of PTEN mutant cancer?... 12/05/2015 - 16/05/2015
    36  Functional characterization of genomic abnormalities that cooperate with EGFR and K-Ras oncogenic mu... 11/05/2015 - 12/05/2015
    37  Myc drives Pten/p53-deficient proliferation and metastasis due to Il6-secretion and Akt-suppression ... 18/04/2015 - 22/04/2015
    38  p53psi is a neomorphic p53 isoform that reprograms cells towards the acquisition of metastatic featu... 14/08/2012 - 18/08/2012
    39  SOCS2 leads to EGFR TKi resistance in lung cancer by activating IL-6 mediated signaling... 14/08/2012 - 18/08/2012
    40  Substrate specifity of receptor tyrosine kinases is critical for selective signaling... 14/08/2012 - 18/08/2012
    41  The Effects of Telomerase Inhibitor GRN163L (Imetelstat) On Cell Cytoskeleton and Cell Cycle... 28/10/2009 - 31/10/2009
    42  Effect of Akt pathway inhibitors in HCC: a novel target for treatment... 03/09/2009 - 06/09/2009
    43  The Effects of Telomerase Inhibitor "GRN163L" on Different Cell Lines... 11/07/2009 - 16/07/2007
    44  TGF-beta induces senescence in epithelial-like hepatocellular carcinoma cells... 21/05/2009 - 24/05/2009
    45  Downregulation and the anti-growth effect of Zeb2 in hepatocellular carcinoma... 21/05/2009 - 24/05/2009
    46  Molecular Mechanisms of TGF-beta-induced senescence in hepatocellular carcinoma... 29/10/2008 - 01/11/2008
    47  TGF-beta induces p53/Rb-independent, but oxidative stress-dependent cellular senescence in hepatocel... 05/10/2007 - 07/10/2007
    48  SMAD interacting protein 1 (SIP-1) acts as a negative regulator of growth in hepatocellular carcinom... 05/10/2007 - 07/10/2007
    49  Senescence induction as a potential therapeutic strategy in hepatocellular carcinoma... 13/09/2007 - 16/09/2007
    50  Induction of senescence as a potential therapeutic strategy in hepatocellular carcinoma... 09/07/2007 - 10/07/2007
    51  Role of SMAD interacting protein 1 in reprogramming of replicative senescence... 24/03/2007 - 26/03/2007
    52  Role of TGF-beta and ROS signaling pathways in hepatocellular senescence... 24/03/2007 - 26/03/2007
    53  Induction of replicative senescence in hepatocellular carcinoma cells... 24/06/2006 - 29/06/2006
    54  TGF-beta Signaling and Hepatocellular Senescence... 22/06/2006 - 24/06/2006
    55  Role of TGF-beta signaling in hepatocellular senescence... 22/06/2006 - 24/06/2006
    56  Characterization of TGF-beta-induced Early Senescence in Hepatocellular Carcinoma Cell Lines... 26/03/2006 - 31/03/2006
  • NO BÖLÜM ADI YIL
    1  CRISPR/Cas9 Gene Editing in Mammalian Cells Using LentiCRISPRv2/LentiGuide-Puro Vectors CRISPR-Cas Methods...  2021
    2  Inducible CRISPR-Based Genome Editing for the Characterization of Cancer Genes Genome Editing and Engineering...  2018
  • NO AD YIL
    1  TÜBA Üstün Başarılı Genç Bilim İnsanı...  2017
    2  Bilim Akademisi Genç Bilim İnsanı...  2019